Document 1922
 DOCN  M94A1922
 TI    Social and behavioral research in HIV vaccine trials in Rwanda:
       identification of priorities.
 DT    9412
 AU    Gasekurume J; Saba J; Souteyrand Y; Ferry B; Ntereye P; N'Sengimana J;
       Raynaut C; PAMEVA, Kigali, Rwanda.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):420 (abstract no. PD0290). Unique
       Identifier : AIDSLINE ICA10/94370653
 AB    OBJECTIVES: As Rwanda is one of the four sites selected by WHO for HIV
       Vaccine Development, Social and Behavioral Research was identified as an
       essential component in preparation of future HIV Vaccine Efficacy
       Trials. Major social, behavioral and psychological issues related to
       these trials have to be adressed in order to define research priorities.
       METHODS: A workshop was held by the National Plan for HIV Vaccine
       Development in Kigali and supported by WHO. It involved all social
       scientists of the country working on AIDS as well as consultants from
       WHO and the National Agency for Research on AIDS in France. The outcome
       was reached, in three steps: a brainstorming on the issues to be
       addressed in Rwanda, identification of major research directions and
       specific research projects ranked according to their priority. RESULTS:
       Three research directions including seven research projects that should
       be developed in priority were identified: 1) Assessment of level of
       information, opinions and attitudes in the population (perception of HIV
       infection and AIDS: perception of vaccines and HIV vaccine trials and
       analysis of the impact of formal and informal information channels
       related to HIV, AIDS, and Vaccines). 2) Volunteering in the trials and
       Informed Consent issues (social and behavioral analysis of decision
       taking with respect of individual health problems and prevention:
       assessment of individual and community acceptability of trial
       participation). 3) Sexual behaviour and risk taking (context and factors
       associated with sexual behaviour and risk taking: monitoring sexual and
       behavioral change in target populations recruited in the epidemiological
       studies in preparation for future HIV Vaccine Efficacy Trials).
       DISCUSSION AND CONCLUSIONS: Social and behavioral research is one of the
       major components of HIV Vaccine Research and field strengthening. Close
       collaboration between social scientists, epidemiologists, biologists and
       clinicians is essential in preparation for future HIV Vaccine Efficacy
       Trials. Such workshop helps scientists in setting up appropriate studies
       to better understand attitudes and behaviours of the populations that
       might benefit of HIV Vaccine. These studies are planned to start in
       Rwanda 1994.
 DE    Acquired Immunodeficiency Syndrome/*PREVENTION & CONTROL/  PSYCHOLOGY
       *AIDS Vaccines  Clinical Trials/*STANDARDS  France  Human  HIV
       Infections/*PREVENTION & CONTROL/PSYCHOLOGY  Informed Consent  Research
       Support  Risk-Taking  Rwanda  Sex Behavior  World Health Organization
       MEETING ABSTRACT

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